on - invasive assessment of inflammatory burden in small abdominal aortic aneurysms: A USPIO - enhanced Magnetic Resonance Imaging (MRI) study - USPIO enhanced MRI of AAAs

Cambridge University Hospitals NHS Foundation Trust0 个研究点目标入组 0 人开始时间: 2009年4月9日最近更新: 2019年6月30日

试验速览

暂无简介。

•1. All patients aged 18-90 years with small infra-renal AAAs (> 4.0 cm to < 5.5 cm), which are either newly detected or under regular surveillance and which are not being considered for surgery or endovascular treatment.
•2.Female subjects must be of non-childbearing potential (post-menopausal females who have been amenorrheic >1 year, or pre-menopausal females with a documented hysterectomy or bilateral oophorectomy.
•3. Signed written informed consent prior to beginning study related procedures (subject must understand the aims, investigational procedures and possible consequences of the study).
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years)
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years)
•F.1.3.1 Number of subjects for this age range

•1. History of atopy, asthma, allergic reaction to contrast materials.
•2. Known and documented history of renal impairment
•3. Known and documented history of haemochromatosis
•4. Contraindication to MRI imaging including but not limited to:
•a)Intracranial aneurysm clips (except Sugita) with an appropriate operative conformation
•b)History of intra- orbital metal fragments that have not been removed by an MD
•c)Pacemakers and non-MR compatible heart valves
•d)Inner ear implants
•e)History of claustrophobia in MR
•5. Inability to give informed consent

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