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Evaluating the systemic level of inflammation in Relation to the perioperativ Outcome of Patients with pre-existing cardiovascular diseases in non-cardiac surgery

Recruiting
Conditions
Aneurysms of the descending thoracic aorta and/or abdominal aorta
Registration Number
DRKS00029162
Lead Sponsor
Charité Campus Benjamin FranklinKlinik f. Anästhesiologie m. S. operative Intensivmedizin
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

planned, open vascular surgery of the aorta
Revised Cardiac Index >=2

Exclusion Criteria

Pregnancy, lactation, participation in any other prospective interventional study during participation in this study.
Patients who are incapable of giving consent.
Patients who are in hospital because of an administrative order.

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
This pilot study - in the context of clinical routine - is intended to estimate the effect and the case number planning for subsequent studies.<br>The following endpoints will be registered: Vital signs and their indices (oxygen saturation, blood pressure, heart rate, heart rhythm, cardiac index, stroke volume, stroke volume variation, stroke volume index, pulse pressure variation, central venous pressure, lactate, base excess, haemoglobin content, creatinine concentration, central venous saturation, diuresis), duration of surgery, anaesthesia duration, ventilation duration, ventilation parameters, intraoperative blood loss, need for blood products, catecholamine doses, incidence of organ complications, duration of dialysis, echocardiography parameters (presence of pericardial effusion, size of atria and ventricles, presence of vitia, ejection fraction, assessment of heart valves), cytokine levels, length of stay (ICU, hospital).
Secondary Outcome Measures
NameTimeMethod
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