A study of how workers with occupational asthma breathe out forcefully and quickly (peak expiratory flow)

Not Applicable

• Conditions: Respiratory; Occupational asthma

• Registration Number: ISRCTN95990788
• Lead Sponsor: niversity Hospitals Birmingham NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-31
• Last Update Posted: 15 July 2024
• Study Completion: 2026-08-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Records from all workers with possible occupational asthma who have kept frequent measurements of their breathing using peak flow meters over several weeks at work and at home as part of their investigation to confirm their diagnosis and who have at least one positive score for occupational asthma, will be identified from the Oasys database on NHS trust computers (derived from- and part of the electronic patient record) from 1990 to the present day

Exclusion Criteria

1. Patients for whom PEF records were inadequate for analysis (eg. too few readings, insufficient number of days at work)
2. Records of patients whose occupational exposures are unknown

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The ABC score from the Oasys program for the PEF study measured using patient records

Secondary Outcome Measures

Name	Time	Method
Measured using patient records at a single time point:<br>1. Differences in the pattern of reaction (immediate, flat, late)<br>2. Recovery time (1,2, >2 days)<br>3. Diurnal variation in PEF home vs work<br>4. Sensitivity and specificity of questionnaire responses (for the questionnaire analysis)