Expiratory pressure for severe acute respiratory distress syndrome with V-V ECMO respiratory support trial
Not Applicable
Recruiting
- Conditions
- Acute respiratory distress syndromeARDS, acute respiratory distress syndrome, ECMO, extracorporeal membrane oxygenationD012128
- Registration Number
- JPRN-jRCT1062220062
- Lead Sponsor
- Ohshimo Shinichiro
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 210
Inclusion Criteria
Adult patients (18-80 years old) with ARDS requiring V-V ECMO
Exclusion Criteria
1. Had been converted from V-A ECMO
2. Had been on a ventilator for longer than 7 days
3. Hemodynamically unstable with LVEF below 40 percent
4. Pneumothorax or air leak syndrome
5. ARDS due to thoracic trauma
6. ARDS due to extra-pulmonary reason
7. Known pregnancy
8. Were judged by the ICU attending doctors as being unsuitable to participate in this study based on their medical condition
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ECMO-free days during the first 28 days
- Secondary Outcome Measures
Name Time Method mortality at 28 days, in-hospital mortality at 60 days, ventilator-free days during the first 60 days, length of ICU stay