Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury
- Conditions
- Postoperative Acute Kidney Injury
- Interventions
- Other: No intervention
- Registration Number
- NCT06462755
- Lead Sponsor
- Chinese PLA General Hospital
- Brief Summary
To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population.
The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation.
Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 57089
- elderly patients (aged ≥ 65 years) undergoing non-cardiac surgeries
- (1) Patients who underwent endoscopic or transplant procedures;
- (2) Patients who underwent surgeries lasting longer than 10 hours;
- (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels ≥ 353.6 μmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) < 15 ml/min per 1.73 m2;
- (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description elderly patients (aged ≥ 65 years) No intervention elderly patients undergo surgeries
- Primary Outcome Measures
Name Time Method Number of participants with postoperative acute kidney injury within seven days following surgery Postoperative acute kidney injury
- Secondary Outcome Measures
Name Time Method