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Clinical Trials/NCT05245123
NCT05245123
Completed
N/A

Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families

Universitätsklinikum Hamburg-Eppendorf2 sites in 1 country100 target enrollmentFebruary 21, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Neuroblastoma
Sponsor
Universitätsklinikum Hamburg-Eppendorf
Enrollment
100
Locations
2
Primary Endpoint
Health-related Quality of Life of the parents (SF-12)
Status
Completed
Last Updated
last year

Overview

Brief Summary

Families of children with rare diseases (i.e., not more than 5 out of 10.000 people are affected) are often highly burdened with fears, insecurities and concerns regarding the affected child and his/her siblings. The aim of the present research project is to examine the psychosocial burden of the children with rare solid abdominal tumors and their family in order to draw attention to a possible psychosocial care gap in this population.

Detailed Description

The central objective of the cross-sectional study is to show the psychosocial supply gap for families with children and adolescents affected by rare diseases in the field of oncology pediatric surgery. Among the rare diseases that are included are rare solid abdominal tumors. In order to have a comparative sample, additional data of a matched control group are collected. Central standardized psychosocial outcomes will be assessed from the perspectives of the parents and the affected child.

Registry
clinicaltrials.gov
Start Date
February 21, 2022
End Date
March 31, 2023
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Johannes Boettcher

Principal Investigator

Universitätsklinikum Hamburg-Eppendorf

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Health-related Quality of Life of the parents (SF-12)

Time Frame: 4 minutes

Health-related Quality of Life (HRQoL) of the parents, assessed from the perspective of the parents by the "Short-Form-12" (SF-12; Morfeld, Kirchberger \& Bullinger, 2011). The instrument consists of 12 items. Higher scores indicate greater HRQoL.

Severity of generalized anxiety disorder

Time Frame: 1 minutes

Generalizied Anxiety Disorder Scale-7 (GAD-7; Spitzer, Kroenke \& Löwe, 2006). The instrument consists of 7 items. Higher score indicate greater anxiety levels.

Health-related quality of life of the chronically-ill children/adolescents (Peds-QL 4.0)

Time Frame: 4 minutes

Health-related quality of life of the chronically-ill children/adolescents, assessed from the perspective of the child/adolescent (from 10 years of age) and from the perspective of the parents by the "Pediatric Quality of Life Inventory 4.0" (Peds-QL 4.0; (Varni, Seid, \& Kurtin, 2001). Items will be linearly transformed to a scale of 0 to 100, with higher scores indicating better HRQoL.

Psychiatric disorders of the chronically-ill children/adolescents (SDQ)

Time Frame: 4 minutes

Psychiatric disorders of the chronically-ill children/adolescents assessed perspective of the child/adolescent and from the perspective of the parents by the "Strengths and Difficulties Questionnaire" (SDQ; Klasen, Woerner, Rothenberger, \& Goodman, 2003). Items are rated on a three-point Likert scale (0 to 2). Higher scores represent greater psychopathology or greater prosocial behavior.

Severity of depression (PHQ-9)

Time Frame: 2 minutes

Severity of depression, will be assessed with the 9-question Patient Health Questionnaire (PHQ-9; Löwe et al., 2015). The instrument consists of 9 items. Higher scores indicate greater depression levels.

Mental health of the parents (BSI-18)

Time Frame: 4 minutes

Mental health of the parents, assessed from the perspective of the parents by the "Brief Symptom Inventory-18" (BSI-18; Spitzer et al., 2011). The instrument consists of 18 items, which are answered on a five-point Likert scale (0 to 4). Higher BSI scores indicate greater psychological distress.

Quality of Life of the parents (EQ-5D)

Time Frame: 1 minutes

Quality of Life (QoL) of the parents, assessed from the perspective of the parents by the instrument "European Quality of Life Five Dimension" (EQ-5D; Hinz et al., 2006). The instrument consists of 5 dimensions, which are answered on a three-point scale. Higher scores indicate greater QoL.

Secondary Outcomes

  • Family relationships, family dynamics and functionality (FB-A)(3 minutes)
  • Familial predispositions (FaBel)(3 minutes)
  • Social support of the parents, of the chronically-ill children/adolescents (OSSS)(3 minutes)
  • Coping of the parents (CHIP-D)(3 minutes)
  • Parent-child communication (PACS)(4 minutes)
  • Satisfaction with the relationship and parenting relationship of the parents (PFB)(4 minutes)

Study Sites (2)

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