Effects of Combined Interventions to Optimize Recovery During High-intensity Exercises in Healthy Adults

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: ERP; Other: Placebo

• Registration Number: NCT04508738
• Lead Sponsor: Swiss Federal Institute of Technology

Brief Summary

The objective of the study is to evaluate the effects a complex recovery intervention during the breaks of a repeated sprint test on exercise performance compared to placebo and control conditions. The enhanced recovery package (ERP) includes neck cooling with an iced gel pad, drinking a 6% CHO solution, mouth-rinsing with a 10% CHO, 6 mg･kg -1 caffeine solution, performing submaximal squats and hyperventilating a hyperoxic mixture; all applied in each 3-min break in-between the six 30-s sprints. This intervention will be compared to a placebo and a control condition.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-08-04
• Study First Submitted QC: 2020-08-07
• Study First Posted: 2020-08-11
• Study Start: 2020-09-10
• Status Verified: 2020-10
• Primary Completion: 2021-06-30
• Study Completion: 2021-06-30
• Last Update Submitted: 2021-06-30
• Last Update Posted: 2021-07-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 16

Inclusion Criteria

• Informed Consent as documented by signature (Appendix Informed Consent Form)
• Healthy
• Male
• Age: 18-40 years
• Body-Mass-Index (BMI): 18.5-24.9 kg･m-2
• Trained individuals: max. Power output ≥ 4.0 Watts･kg-1
• Non-smoking
• Willingness to adhere to the study rules

Exclusion Criteria

• Known or suspected non-compliance, drug or alcohol abuse
• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participants
• Previous enrolment into the current study
• Intake of medications affecting performance or the respiratory, cardiovascular or neuromuscular system
• Acute or chronic illness affecting performance or the respiratory, cardiovascular or neuromuscular system

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
ERP Intervention	ERP	Combination of different methods to improve recovery.
Placebo	Placebo	A combination of methods similar to the ERP intervention but at an intensity / mixture supposed to be ineffective at improving recovery.

Primary Outcome Measures

Name	Time	Method
Change in mean power output	through study completion, an expected average of 3 weeks per participant	Measured over the six 30s high-intensity cycling sprints in each of the three conditions. Mean power mirrors the body's ability to generate muscle power and physical energy. Any meaningful effects of the recovery interventions will eventually translate into a higher power output.
Change in fatigue index	through study completion, an expected average of 3 weeks per participant	Fatigue index = drop in power output from the beginning to the end a 30s sprint test. The change in this index will be calculated from the 1st to the 6th sprint test in each condition.

Trial Locations

Locations (1)

ETH Zürich, Exercise Physiology Lab; 🇨🇭 Zürich, ZH, Switzerland