A clinical trial to study the effect of vitamin D in improving the symptoms of heartburn and regurgitation in patients with Gastroesophageal reflux disease
Phase 2
- Conditions
- Health Condition 1: null- patients with gastro esophageal reflux disese and vitamin D deficiency
- Registration Number
- CTRI/2014/11/005183
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients diagnosed with Gastroesophageal reflux disease based on the clinical diagnostic criteria
2.Patients giving consent for their inclusion in the study
3.BMI < 30 kg/m²
Exclusion Criteria
1.Patient previously operated for GERD
2.Patients who have received mega doses (6,00,000 IU) of Vit D in the last 6 months
3.Patients having Peptic stricture, GOO, primary Systemic Sclerosis, Endoscopic Sclerotherapy, EVL, Esophageal varices
4.Women who are pregnant/lactating or planning conception; students; trainees; mentally retarded; institutionalised subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Esophageal motor function <br/ ><br>Improvement in symptomatologyTimepoint: 4 weeks
- Secondary Outcome Measures
Name Time Method Improvement of quality of life <br/ ><br>Improvement in skeletal muscle functionTimepoint: 4 weeks