Effects of vitamin D and calcium supplementation on bone mineral density among Thai MSM adolescents with pre-exposure prophylaxis
Not Applicable
Recruiting
- Conditions
- healthy MSM/TG adolescents aged between 15ᆬ years
- Registration Number
- TCTR20190624002
- Lead Sponsor
- Faculty of Medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 100
Inclusion Criteria
-MSM/TGW
-At risk population of HIV infection (at least 1 as follow)
Multiple partner (> 1 partner during past 6 months)
Condomless sex
Serodiscordant couple
-age 15-24 years
-Desired to received PrEP
-anti-HIV: negative
Exclusion Criteria
-Acute retroviral syndrome
-History of bone fracture
-Received Ca > 1,000 mg/day within 6 months before enrollment
-Received vitaminD > 400 IU/day within 6 months before enrollment
-History of growth hormone def./growth hormone used
-History of endocrinopathy including primary hyperparathyroidism, hypoparathyroidism, cushing syndrome
-Abnormal renal function test (Cr clearance < 60 ml/min/1.73m2)
-History of steroid used in past 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method effect of vitamin D and calcium supplement on bone mass density 6 months %BMD change
- Secondary Outcome Measures
Name Time Method effect of TDF/FTC on bone mass density 6 months %BMD change