Comparative study of Letrozole vsGanirelix acetate in ovarianhyperstimulation syndrome (OHSS)
- Conditions
- Health Condition 1: N00-N99- Diseases of the genitourinary system
- Registration Number
- CTRI/2020/10/028674
- Lead Sponsor
- Ankoor Fertility Clinic
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 105
Body mass index is 18 to 29
USG pelvis normal with presence of both ovaries
AFC > 20 (More than 20 follicles developing on folliculometry)
AMH > 5
Basal levels of oestradiol (<= 50 pg/ml) on day 1 of stimulation
Serum estradiol level > 4000 pg/ml on the day of trigger
All patients had to sign an informed consent and Review Board permission was obtained
Number of oocyte retrieval >25;
Estradiol level > 3500 pg/mL on the day of trigger
Clinical or ultrasonography proven OHSS on the day of oocyte retrieval, such as
ultrasonographic evidence of ascites.
Ovary diameter 10cm on one or both sides on day 3 after oocyte retrieval
Puncture follicle number should be 30 (follicular diameter14mm on oocyte retrieval day)
1.All women with serum estradiol levels < 2500 on day of trigger
2.Not receiving dual trigger
3.Contraindications to study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method