Prospective Observational Study on Incidence of Invasive Fungal Infections Among Patients With Acute Lymphoblastic Leukemia Ph-negative

Recruiting

• Conditions: Invasive Fungal Infections; Acute Lymphoblastic Leukemia, Adult
• Interventions: Other: observation of invasive fungal infections

• Registration Number: NCT05750706
• Lead Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Brief Summary

The study aims to evaluate incidence of invasive antifungal infections among patients with acute lymphoblastic leukemia Ph negative during the first weeks of treatment

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-01
• Status Verified: 2023-02
• Study First Submitted: 2023-02-20
• Study First Submitted QC: 2023-02-20
• Last Update Submitted: 2023-02-20
• Study First Posted: 2023-03-02
• Last Update Posted: 2023-03-02
• Primary Completion: 2023-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• diagnosis of acute lymphoblastic leukemia Ph negative
• age more than 18 yo

Exclusion Criteria

• diagnosis of acute lymphoblastic leukemia Ph positive
• acute lymphoblastic leukemia relapsed/refractory
• lymphoblastic lymphoma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Acute lymphoblastic leukemia, invasive fungal infection	observation of invasive fungal infections	-

Primary Outcome Measures

Name	Time	Method
Incidence of invasive fungal infections during first week of chemotherapy	18 months

Secondary Outcome Measures

Name	Time	Method
Mortality rate among patients with invasive fungal infections	30 months

Trial Locations

Locations (1)

Fondazione Policlinico Universitario A. Gemelli IRCCS; 🇮🇹 Rome, Italy