The Predictive Ability of Glycated Albumin Combined With Body Composition for Gestational Diabetes Mellitus Diagnosis
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Area under the curve of GA combined with body composition for GDM diagnosis
研究概览
简要总结
This study is going to investigate the predictive ability of glycated albumin combined with body composition, including body weight, BMI, fat free mass and fat mass for gestational diabetes mellitus (GDM) diagnosis.
详细描述
The prevalence of GDM is increasing all over the world. It has bad influence for both pregnant women and fetus. Early treatment is useful for GDM prevention. Therefore early screening is important for healthcare doctors to detect the potential patients. Glycated albumin (GA) is an optimal index for blood glucose evaluation compared to HbA1c, however it may be influenced by body weight and composition. The investigators are going to investigate the predictive ability of glycated albumin combined with body composition, including body weight, BMI, fat free mass and fat mass for gestational diabetes mellitus (GDM) diagnosis. This study recruit pregnant women before 12 weeks of their pregnant age and test GA level and body composition via bioelectrical impedance analysis. During 24-28 weeks of pregnant age, all participants will do the glucose tolerant test for GDM diagnosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 22 Years 至 45 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age between 20-45
- •Healthy, without heart disease, liver or kidney dysfunction, immune system or metabolic or infectious disease,
排除标准
- •Diabetes that appeared before pregnancy
- •Pregnant with medical disease, such as asthma, hypertension, cardiovascular diseases, kidney diseases or liver disease.
- •Hormone use in the recent 1 year
- •Assisted reproduction pregnancy
- •Multiple births
- •Cannot complete the blood test or body composition examination
结局指标
主要结局
Area under the curve of GA combined with body composition for GDM diagnosis
时间窗: May 2021
prediction ability of GA and body compostion
次要结局
- correlative factors for GDM(May 2021)
- GDM prediction model establishment(May 2021)
