Identifikation of arrhythmogenic Substrate using echocardiography and MRI

• Conditions: I48; I47; Paroxysmal tachycardia; Atrial fibrillation and flutter

• Registration Number: DRKS00017088
• Lead Sponsor: Charité Campus Charité Mitte

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-05-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

All patients in which a left atrial of ventricular electroanatomical substrate mapping is performed based on a clinical indication.

Exclusion Criteria

- Pregnancy; Gadolinium-MRI will not be performed if: GFR < 45 ml/min/1.73 m2; intolerance or allergy against Gadolinium contrast agents; application of Gadolinium contrast agents in the preceding 6 months; denial of the Patient; Echo contrast Agent will not be applied if: intolerance or allergy against Gadolinium contrast agents; denial of the Patient

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Agreement of Areas of arrhythmogenic substrate as determined by electroanatomical substrate mapping (reference) vs. periprocedural LGE-MRI.

Secondary Outcome Measures

Name	Time	Method
Agreement regarding identification of atrial scar (incl. localisation) between periprocedural 2D-strain echocardiography, periprocedural LGE-MRI and invasive electroanatomical mapping.