Comparison of efficiency of preoperative single dose tramadol/paracetamol combination between 50/500 VS 75/650 mg on acute postoperative pain after abdominal gynecologic surgery: a randomized controlled trial

Phase 4

• Conditions: Women patients under total abdominal hysterectomy or open myomectomy with/without other operations, cystectomy, ovarian tumor removal, Salpingectomy, Salpingo-oophorectomy; Paracetamol, tramadol, single oral, combination, open hysterectomy, pain

• Registration Number: TCTR20211013003
• Lead Sponsor: Khon Kaen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-13
• Study Completion: 2022-07-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: Female
• Target Recruitment: 74

Inclusion Criteria

1. 18-65 year old women, 2. ASA physical status classification 1-2, 3. undergoing open abdominal benign gynecologic condition

Exclusion Criteria

1. History of study drug allergy, 2. History of chronic pain, liver disease or gastrointestinal bleeding, 3. pregnancy, 4. psychiatric problem

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
24 hr postoperative total morphine consumption 24 hr after operation mg

Secondary Outcome Measures

Name	Time	Method
tim to first morphine requirement 24 hr of study minute,Pain severity 24 hr of study Numeric rating scale,Side effect 24 hr of study PONV severity grading,side effect 24 hr of study Sedation score,side effect 24 hr of study ambulation score