Awake Tracheal Intubation is Associated With Fewer Adverse Events in Critical Care Patients Than Standard Tracheal Intubation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- desaturation
研究概览
简要总结
Tracheal intubation in critical care is a high-risk procedure requiring significant expertise and airway strategy modifications, such as awake intubation with video laryngoscope or flexible endoscope intubation. Furthermore, delayed sequence intubation can be used by experts in certain high-risk subgroups. The investigators hypothesise that awake tracheal intubation is associated with a lower incidence of severe adverse events than standard tracheal intubation in critical care patients.
详细描述
Intubation records from 2020 to 2022 were acquired to examine all tracheal intubations of critical care patients at a tertiary hospital. Each awake tracheal intubation (awake) case - all of which were performed using a videolaryngoscope with a hyperangulated blade - was propensity matched with two controls (1:2 ratio; standard intubation videolaryngoscopy (VL) and direct laryngoscopy (DL) undergoing general anaesthesia), with similar comorbidities and intubations performed after the induction of anaesthesia (asleep).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Data for all critical care patients requiring tracheal intubation during the study period
排除标准
- •included incomplete data reports
结局指标
主要结局
desaturation
时间窗: during intubation procedure (within 30 Minutes)
defined as SpO2 \< 80% after sufficient preoxygenation
Hypotension
时间窗: during intubation procedure (within 30 Minutes)
defined as a mean arterial pressure \< 55 mmHg
cardiac arrest
时间窗: during intubation procedure (within 30 Minutes)
defined as a peri-interventional cardiac arrest
次要结局
- Airway Injury(during intubation procedure (< 120 seconds))
- other adverse events(during intubation procedure (< 120 seconds))
- Cormack and Lehane classification (Class I-IV)(during intubation procedure (< 120 seconds))
- FPS(during intubation procedure (< 120 seconds))
研究者
Marc Kriege, MD
Principal Investigator
Johannes Gutenberg University Mainz