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Clinical Trials/NCT05044416
NCT05044416
Completed
Not Applicable

Tracheal Intubation With VieScope Versus Videolaryngoscopy in Patients for Elective Surgery With an Expected Difficult Airway - a Prospective Randomized Trial (VieScOP-II)

Universitätsklinikum Hamburg-Eppendorf1 site in 1 country58 target enrollmentSeptember 11, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Airway Management
Sponsor
Universitätsklinikum Hamburg-Eppendorf
Enrollment
58
Locations
1
Primary Endpoint
Percentage of Glottis Opening (POGO) scale
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Patients requiring endotracheal intubation for elective surgery with an expected difficult airway are randomized to be intubated either by a) VieScope or b) videolaryngoscopy.

Detailed Description

Tracheal intubation is required for different surgical procedures for mechanical ventilation and to prevent aspiration of secretions. In patients with an expected difficult airway, tracheal intubation is often performed by videolaryngoscopy (VL). However, this technique has limitations and may fail due to insufficient visualization of the larynx. A new device has been introduced that consists of an illuminated straight plastic tube for laryngoscopy (VSC, Vie Scope, Adroit Surgical, Oklahoma City, OK, USA) that enables for indirect intubation over a stylet. So far, the VSC has shown promising results in manikin studies for intubation in normal and difficult airways. We aim to test the VSC in patients compared to videolaryngoscopy in a prospective randomized non-inferiority trial. Patients will be assessed for eligibility in the Anesthesiology Pre-assessment Clinic of the University Medical Center Hamburg-Eppendorf prior to elective surgery. All patients receive a structured preoperative airway assessment. Patients are randomized 1:1 to either intervention or control group. Patients randomized to the intervention group will be intubated with the VSC. Patients randomized to the control group are intubated with a MacIntosh type videolaryngoscope (CMAC, Storz, Germany).

Registry
clinicaltrials.gov
Start Date
September 11, 2021
End Date
June 26, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients requiring general anesthesia with transoral tracheal intubation for elective surgery
  • Preoperative airway assessment reveals an expected difficult airway (rated by the responsible anesthetist in the Pre-assessment Clinic based on the existing in-house algorithm)

Exclusion Criteria

  • Pregnant or breastfeeding woman
  • Confirmed indications for awake fiberoptic intubation especially due to enoral, pharyngeal tumors, abscesses or other processes
  • Planned endotracheal intubation without deep anesthesia or neuromuscular blocking agents (e.g. awake videolaryngoscopy)
  • Required transnasal tracheal intubation (e.g. for surgical reasons)
  • Requirement of special endotracheal tubes such as laser or RAE tubes for surgical reasons
  • Patients at risk for pulmonary aspiration who qualify for rapid sequence induction
  • Loose teeth
  • Denial of consent

Outcomes

Primary Outcomes

Percentage of Glottis Opening (POGO) scale

Time Frame: 15 min

intubating conditions according to the percentage of glottis opening scale (POGO), range 0-100%, higher values better

Secondary Outcomes

  • time to intubation(15 min)
  • first attempt success rate(15 min)
  • Cormack-Lehane(15 min)
  • overall success rate(15 min)
  • hypotension(15 min)
  • hypoxia(15 min)
  • intubation difficulty(15 min)
  • esophageal intubation(15 min)
  • time to successful intubation with one attempt(15 min)
  • number of attempts(15 min)
  • aspiration(15 min)

Study Sites (1)

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