NCT00374621已完成不适用
Randomized Clinical Trial of Cervical Ripening and Labor Induction Using Stepwise Oral Misoprostol With or Without Intravaginal Isosorbide Mononitrate
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 156
- 试验地点
- 1
- 主要终点
- Time to vaginal delivery
研究概览
简要总结
The purpose of this study is to determine the efficacy and safety of the addition of intravaginal isosorbide mononitrate to an established protocol of oral misoprostol for cervical ripening and labor induction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women
- •18 years of age or greater
- •Singleton pregnancy between 32-42 weeks gestation requiring labor induction
- •Membranes must be intact
排除标准
- •Ruptured membranes
- •Gestational age less than 32 weeks
- •Non-reassuring fetal heart rate tracing
研究组 & 干预措施
Misoprostol
Active Comparator
干预措施: Misoprostol with or without isosorbide mononitrate (Drug)
Misoprostol with Isosorbide Mononitrate
Active Comparator
干预措施: Misoprostol with or without isosorbide mononitrate (Drug)
结局指标
主要结局
Time to vaginal delivery
时间窗: First dose of study medication to delivery
次要结局
未报告次要终点
研究者
Yasser Yehia El-Sayed
Professor
Stanford University
研究点 (1)
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