The effect of plasma injection in the ovary on the number of Follicle and oocytes, the quality of oocytes, and Anti Mullerian hormone in cases of poor ovarian function.

Phase 4

Conditions: Female Infertility.
Female infertility

Registration Number: IRCT20141217020351N11

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 44

Inclusion Criteria

The second cycle of embryo transfer
Criteria for detecting poor ovarian function based on the Bologna criterion
Age less than 45 years
History of having at least three oocytes in the previous cycle
AMH hormone less than 1.1 ng / ml
BMI less than 30kg/m2
At least ten million sperm and three percent sperm with a normal morphology

Exclusion Criteria

Immunological diseases
Hematological diseases
Chromosomal or genetic disorder
Uterine disorders
Hemoglobin level less than 11 grams per deciliter
Platelets less than one hundred and fifty thousand per cubic millimeter
Systemic use of corticosteroids within two weeks before the procedure
Hypothyroidism
Respiratory tract infections
Kidney failure
Endometriosis
Sub mucusal myoma
Asherman Syndrome
Pathology of the Fallopian tubes (Hydrosalpinx)
Endocrine diseases
Endocrine diseases
Allergic reactions
The dissatisfaction of the patient to continue treatment
No contraindications for pregnancy

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of oocyte. Timepoint: Two months after the PRP. Method of measurement: Vaginal Sonography.;Antimullerian hormone. Timepoint: Two months after the PRP. Method of measurement: Blood Test.;The quality of oocyte. Timepoint: Two months after the PRP. Method of measurement: Vaginal Sonography.

Secondary Outcome Measures

Name	Time	Method
umber of obtained of embryo. Timepoint: Two months after the PRP. Method of measurement: Embryologist diagnosis.;The quality of resulted embryo. Timepoint: Two months after the PRP. Method of measurement: Embryologist diagnosis.;Chemical Pregnancy. Timepoint: Two weeks after the embryo transfer. Method of measurement: Blood Test.