Platelet-Rich Plasma Injection in acute anal fissure treatment
Phase 3
- Conditions
- ??Anal fissure.Fissure and fistula of anal and rectal regions
- Registration Number
- IRCT20220220054071N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
Patients with acute anal fissure (clinical presentation in less than 6 weeks)
Exclusion Criteria
Patients with anal fissures occurring in more than 6 weeks
Patients with anal fissures in atypical locations
Patients with multiple fissures
Patients with inflammatory bowel disease
cancer patients
patients with sexually transmitted diseases
history of anorectal surgery
patients with immunodeficiency
pregnancy
patients with tuberculosis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patient complaint about anal fissure. Timepoint: one week and one month after the second injection of PRP. Method of measurement: pain, bleeding during defecation, itching and the appearance of the wound from the surgeon's point of view.;Patient pain. Timepoint: one week and one month after the second injection of PRP. Method of measurement: visual analogue scale.
- Secondary Outcome Measures
Name Time Method