Femoral Cartilage Thickness in Knee Osteoarthritis
- Conditions
- Knee Osteoarthritis
- Interventions
- Diagnostic Test: ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality
- Registration Number
- NCT05456711
- Brief Summary
The aim of the study to investigate the relationship between femoral cartilage thickness in Ultrasonographic evaluation and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis
- Detailed Description
Aim: The aim of the study is to investigate the relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis.
Methods: This study is designed as a prospective, cross-sectional trial. 90 participants aged between 50-65 years with knee osteoarthritis(OA) and at least 50 participants without any symptom for knee OA are included in the study in accordance with the inclusion criteria. Participants' demographic characteristics will be evaluated, and ultrasonographic measurement will be performed for measuring femoral cartilage thickness. Visual Analog scale will be used for pain severity and Western Ontario and McMaster Universities Osteoartrit index (WOMAC) will be used for assessing functionality of the patients. Also hematologic parameters(neutrophils, leucocytes, lymphocytes, platelet, CRP, erythrocyte sedimentation rate) will be evaluated for investigating the inflammation. The relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in knee osteoarthritis will be analysed for both group.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 140
- diagnosed as knee osteoarthritis
- aged between 50-65 years
- volunteer to participate in the study
- limitation of cooperation
- moderate to severe dementia or mental retardation, which may cause limitations in examination, testing and treatment
- refusal to participate in the study
- pprevious total knee prosthesis surgery
- secondary osteoarthritis
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description knee osteoarthritis ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality healthy control ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality
- Primary Outcome Measures
Name Time Method Western Ontario and McMaster Universities Osteoarthritis Index 1 day evaluation of functionality
eritrocyte sedimentation rate 1 day eritrocyte sedimentation rate
neutrophil account 1 day neutrophil account
lymphocyte account 1 day lymphocyte account
platelet account 1 day platelet account
Visual Analog Scale 1 day evaluation of pain severity
monocyte account 1 day monocyte account
C-reactive protein 1 day C-reactive protein
ultrasonography 1 day measurement of femoral cartilage thickness
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kanuni Sultan Suleyman Training and Research Hospital
🇹🇷Istanbul, Kucukcekmece, Turkey