Effect of Carbamazepine and Oxcarbazepine on Tinnitus
Phase 2
- Conditions
- nonpulsatile tinnitus.Other diseases of inner ear
- Registration Number
- IRCT138903061138N2
- Lead Sponsor
- Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 57
Inclusion Criteria
1-tinnitus history more than 6 months; 2- The patients 21-65 years with nonpulsatile tinnitus.
Excllusion crateria:1-pulsatile tinnitus 2-mineare's disease 3-vestibular neurinoma 4-otosclerosis 5-the patients use of hearing-aid 6-pregnancy 7- patients with psychologic disorders need to treatment 8-the nontulerance minimal dose of carbamazepine and oxcarbazepine or hypersensitivity to these drugs 9-recent treatment with anti convulsion drugs 10-OCP consumptions and the drugs interaction with carbamazepine but are necessary to patients 10-patients with severe heart disease(CHF,IHD) 11- appearance severe drug hypersensitivity reaction during of treatment
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tinnitus severity. Timepoint: The beginning of treatment and ending of 8th and 12th week. Method of measurement: VAS & TSI.;Quality of Life. Timepoint: The beginning of treatment and ending of 8th and 12th week. Method of measurement: TSI.
- Secondary Outcome Measures
Name Time Method