Emotion recognition training and brain responses

Not Applicable

Completed

• Conditions: ow mood / depression; Mental and Behavioural Disorders; Depressive episode

• Registration Number: ISRCTN50125738
• Lead Sponsor: niversity of Bristol (UK)

Brief Summary

2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32063231 (added 21/02/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-01-21
• Study Completion: 2013-05-30
• Last Update Posted: 3 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Aged between 18 and 40 years
2. Participants who score 14 or higher on the Beck Depression Inventory (BDI)-II
3. English as first language or equivalent level of fluency
4. Right-handed (as assessed by Edinburgh Handedness Inventory)
5. Able to give informed consent as judged by lead researcher

Exclusion Criteria

1. Primary anxiety disorder, psychosis, bipolar disorder or substance dependence [other than nicotine and caffeine] as defined by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)
2. Current use of illicit drug (except cannabis)
3. Being at clinically significant risk for suicidal behaviour
4. Use of psychotropic medication in last 5 weeks prior to study
5. Major somatic or neurological disorders and concurrent medication which could alter emotional processing (including active treatment with counselling, cognitive behavioural therapy or other psychotherapies). We will allow intermittent use of medication, judged by the principal investigator.
7. Participants who have contra-indication for magnetic resonance imaging (MRI) imaging
8. Participants unable to tolerate the scanner environment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eural response to emotional cues: Blood oxygen level dependent (BOLD) responses to emotional facial expression at baseline and one week.