Association Between Environmental Pollutants and Their Effects on Respiratory
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- Association of respiratory symptoms with exposure to pollutants and pollen
研究概览
简要总结
In Latin America and the Caribbean, more than 100 million people are exposed to higher levels of pollution than those recommended by WHO. The objective of the study is to determine the relationship between exposure to environmental pollutants and the prevalence and exacerbation of respiratory allergy. It is an observational, prospective, longitudinal and descriptive study that will include subjects older than 6 years who come to the consultation of the Regional Center for Allergy and Clinical Immunology with a diagnosis of respiratory allergy, positive skin tests and who live in Monterrey and its metropolitan area. After verbal assent, the subject's address and work area will be registered, the Rhinitis Control Assessment Test and the Asthma Control Test as well as spirometry will be made. The geolocation of industries and avenues near the address and work area of subjects will be carried out, as well as the determination of pollutants and pollens by the Integral Monitoring System (SIMA) and the Pollen Sense device. Subsequently, the correlation between exposure to pollutants and respiratory allergy will be analyzed. Dispersion models will be built considering pollutants and climatic factors (precipitation, wind speed, humidity and temperature). By carrying out this project, it will be possible to contribute to the identification of the factors that lead to the development and exacerbation of allergic respiratory diseases and subsequently propose the implementation of measures for their control and recommendations for prevention to the population.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 —(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects over 6 years of age who attend the the Regional Center of Allergy and Clinical Immunology of the University Hospital "Dr. José Eleuterio González "with a diagnosis of respiratory allergy (allergic rhinitis and asthma) and type I immunological hypersensitivity demonstrated by skin tests by an allergist; and who live in the city of Monterrey and its metropolitan area.
排除标准
- •Subjects for whom it is not possible to perform a pulmonary function test or who have concomitant diseases such as COPD, heart disease or some other pathology that, in the opinion of the investigator, may cause confusion with respiratory symptoms. Patients with negative skin tests to aeroallergens.
结局指标
主要结局
Association of respiratory symptoms with exposure to pollutants and pollen
时间窗: 1 year
To determine the relationship between exposure to environmental pollutants and the prevalence and exacerbation of respiratory allergy.
次要结局
- Avenues with highest diesel exhaust particles and traffic related particles(1 year)
- Location of the main industries that emit pollutants(1 year)
- Distance of greater exposure to pollutants(1 year)
- Time of pollutant exposure and association with respiratory symptoms(1 year)
研究者
Cindy Elizabeth de Lira-Quezada
Professor of Allergy and Clinical Immunology
Medicina
