Cortical Excitability and Role of rTMS in Cannabis Use Disorder

Early Phase 1

• Conditions: Cannabis Use Disorder, Moderate

• Registration Number: NCT04106336
• Lead Sponsor: Assiut University

Brief Summary

Repetitive transcranial magnetic stimulation (rTMS) and cortical excitability have a role in cannabis use disorder

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-09
• Study First Submitted: 2019-09-23
• Study First Submitted QC: 2019-09-25
• Last Update Submitted: 2019-09-25
• Study First Posted: 2019-09-27
• Last Update Posted: 2019-09-27
• Study Start: 2019-10-01
• Primary Completion: 2020-10-01
• Study Completion: 2020-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• 18to 50 years of age
• cannabis use disorder according to DSM 5 definition
• clear consent to participate in study

Exclusion Criteria

• cardiac peacemaker
• metal implant in the head as participate will be applied to magnetic field of TMS
• current intake of any medication affect cognition (as anti psychotic and anti epileptic)
• current history of neurological , psychiatric or general medical disease .current or previous drug (other than cannabis )or alcohol abuse or participation in another trial during the past 8 weeks .
• age younger than 18 and older than 50 years

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Determination of role of rTMS for reducing cannabis craving	1 year	Incidenc of cannabis craving after rTMS

Secondary Outcome Measures

Name	Time	Method
Estimation of cortical excitability in cannabis addict	1 year	Incidence of cannabis craving after cortical excitability