NCT04106336UnknownPhase 1
Cortical Excitability and Role of rTMS in Cannabis Use Disorder
Conditions
Interventions
Trial Snapshot
- Phase
- Phase 1
- Sponsor
- Assiut University
- Enrollment
- 60
- Primary Endpoint
- Determination of role of rTMS for reducing cannabis craving
Study Overview
Brief Summary
Repetitive transcranial magnetic stimulation (rTMS) and cortical excitability have a role in cannabis use disorder
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 50 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •18to 50 years of age
- •cannabis use disorder according to DSM 5 definition
- •clear consent to participate in study
Exclusion Criteria
- •cardiac peacemaker
- •metal implant in the head as participate will be applied to magnetic field of TMS
- •current intake of any medication affect cognition (as anti psychotic and anti epileptic)
- •current history of neurological , psychiatric or general medical disease .current or previous drug (other than cannabis )or alcohol abuse or participation in another trial during the past 8 weeks .
- •age younger than 18 and older than 50 years
Arms & Interventions
non cannabis addict
No Intervention
30 non cannabis addict will be control group
cannabis addict
Active Comparator
30 cannabis addict will undergo rTMS
Intervention: rTMS (Device)
Outcomes
Primary Outcomes
Determination of role of rTMS for reducing cannabis craving
Time Frame: 1 year
Incidenc of cannabis craving after rTMS
Secondary Outcomes
- Estimation of cortical excitability in cannabis addict(1 year)
Investigators
Asmaa Omar Radwan Helal
Asmaa Omar Radwan Helal
Assiut University
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