Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function
Not Applicable
Withdrawn
- Conditions
- Kidney Failure, Acute
- Registration Number
- NCT00117416
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
The purpose of this study is to evaluate the renal perfusion depending on the MAP.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Over 18 years old
- Intensive care patient
- Treated with vasopressor
- Given informed consent
- Arterial infusion
- A bladder catheter
Exclusion Criteria
- Anamneses of hypertension
- Neurological trauma
- Acute renal insufficiency other than prerenal or acute tubular necrosis etiology
- Hepatorenal syndrome
- Treated with diuretics
- Mechanical ventilation and unstable
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method creatinine clearance after 4 hours
- Secondary Outcome Measures
Name Time Method resistance index urinary indices of renal function diuresis
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link MAP to renal perfusion in acute kidney failure?
How does MAP management compare to standard-of-care in critically ill patients with acute kidney failure?
Which biomarkers correlate with MAP-induced renal perfusion changes in patients with reduced renal function?
What adverse events are associated with MAP adjustments in acute kidney failure patients?
Are there combination therapies that enhance renal perfusion alongside MAP optimization in acute kidney failure?
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium
University Hospital Ghent🇧🇪Ghent, Belgium