A survey of wound probing effectiveness on surgical site infection in patients with perforated appendicitis
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 114
研究概览
简要总结
Background: While advances have been made in infection control practices, including prophylactic and sterile methods, surgical site infections remain a substantial cause of morbidity, prolonged hospitalization, and death. But in the age of antibiotic resistance and in order of preventing wound infection, various local methods have been devised. Wound probing is one of them that needs for more investigations.
Material and methods: A total of 114 patients with perforated appendicitis were included in this single blind clinical trial. All of them were given standardized preoperative antibiotic and underwent appendectomy through Mc-burney incision with primary closure. They were randomized into two equal groups of control (A) and wound probing (B). In control group we only used simple daily dressing and in probing group we used a cotton-tipped swab for probing between stitches every morning. Our follow-up for assessing wound infection was at 1 week and 3 weeks after discharge.
Results: Of the 114 patients enrolled in this study, there were eleven (9.6%) wound infection (seven in group A and four in group B). In the base of our survey, although the patients in probing group had a lower wound infection (7%) in comparison with control group (12.3%), but statistic analysis did not demonstrate any significant difference (p > 0.05). Hospitalization length and charge, and wound healing were similar between two groups.
Conclusion: Use of surgical wound probing in patients underwent appendectomy for perforated appendicitis has no significant effect in preventing wound infection.
Keywords: Wound infection, Prophylaxis, Perforated appendicitis, Primary closure, Wound healing
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 12 years 至 60 years（—）
- 性别
- All
入选标准
- •1.Ages between 12-60 years old; 2.Operation via Mc-Burney incision due to acute appendicitis; 3.Evidences of perforated appendicitis e.g., a hole, fecalith, abscess or puss observed by surgeon.
- •Exclusion criteria: 1.Non perforated appendicitis; 2.Incision other than Mc-Burney; 3.Pregnancy; 4.Ages less than 12 years old and more than 60 years old; 5.Severe sepsis and Immunodeficiency, diabetes, cardiovascular or renal or respiratory or hepatic insufficiency; 6.Body mass index higher than 30.
排除标准
- 未提供