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临床试验/NCT02127164
NCT02127164已完成不适用

Prospective Evaluation of Wound Management Using Vacuum Assisted Instillation Therapy in Emergent Contaminated Abdominal Surgeries

University of Arizona2 个研究点 分布在 1 个国家目标入组 18 人开始时间: 2014年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
18
试验地点
2
主要终点
Rate of Surgical Site Infection

研究概览

简要总结

Emergent abdominal surgeries have very high rate of wound contamination due to exposure to bacteria from GI tract. There are several different approaches to wound management in these patients including wet-to-dry dressing or application vacuum assisted device on the wound. The investigators propose using the vacuum assisted device with Dakin's solution on patients undergoing emergency surgery for hollow viscus perforation installed immediately at the end of operation and remained there for the first 3 postoperative days, followed by delayed primary closure on postoperative day 4. The investigators believe this technique can achieve earlier wound closure, decrease patient discomfort, improve cost savings, and potentially standardize and revolutionize the investigators management of heavily contaminated wounds.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Emergent surgery involving hollow viscus perforation or necrotic bowel
  • Admitted to the University of Arizona Medical Center, Tucson, AZ

排除标准

  • Prisoners
  • Pregnancy
  • Patients with allergy to Dakin's (sodium hypochlorite) solution.

结局指标

主要结局

Rate of Surgical Site Infection

时间窗: 2 weeks

Surgical site infection is defined as the presence of localized inflammatory signs such as hyperthermia, erythema, tenderness, or purulent discharge that results in positive cultures, along with positive wound cultures. Surgical site can also be regarded as infected based on the individual discretion of the treating physician. Surgical sites with \>10\^5 colonization in swab will be considered contaminated.

次要结局

  • Wong-Baker Faces Pain Rating Scale(1 week)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Andrew Tang

Assistant Professor

University of Arizona

研究点 (2)

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