Survey research on the effects of statin alone or a combination of statin and EPA on endothelial function in patients with type 2 diabetes complicated with dyslipidemia
- Conditions
- type 2 diabetes
- Registration Number
- JPRN-UMIN000005783
- Lead Sponsor
- The Department of Diabetes, Endocrinology and Metabolism, Tokyo Medical University
- Brief Summary
In patients with type 2 diabetes and receiving statin therapy whose LDL-C level was less than 100 mg/dL, the addition of highly purified EPA for 6 months significantly improved vascular function.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Not provided
Those patients who meet any of the following conditions were excluded from the current study: 1) Currently suffer from cerebral hemorrhage or have had it in the past 2) Have embolism or hemorrhagic infarction 3) Are currently suffering from a hemorrhage (conditions such as hemophilia, capillary fragility, hemorrhage from the digestive system, urinary tract hemorrhage, hemoptysis, and vitreous hemorrhage) 4) Have severe congestive heart failure 5) Have a history of hypersensitivity to statin or components of EPA 6) Have a peptic ulcer 7) Have a severe hematological anomaly 8) Have a severe complication (such as a malignant tumor, liver cirrhosis, renal failure and heart failure) 9) Those who failed to give informed consent 10) Other patients whom the chief investigator or attending physician finds unsuitable
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method