SPECTRE-study
Completed
- Conditions
- Barrett's esophagus, esophageal cancer, field cancerization
- Registration Number
- NL-OMON21436
- Lead Sponsor
- Academic Medical Center (AMC) Amsterdam
- Brief Summary
one yet
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Age > 18 years.
- Known BE, defined as columnar lined epithelium of the esophagus containing intestinal metaplasia upon biopsy.
Exclusion Criteria
- Contraindications for ER and/or obtain biopsies (e.g. due to anticoagulation, coagulation disorders, esophageal varices).
- Presence of an advanced lesion (e.g. type 0-I or type 0-III) not amendable for endoscopic resection (T1b).
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of our study is to evaluate the feasibility of using MDSFR combined with OCT for the detection of field cancerization in Barrett esophagus patients.
- Secondary Outcome Measures
Name Time Method The secondary objective is to investigate the biological background of field cancerization detected by ESS