Marijuana for HIV-Related Peripheral Neuropathy

Phase 1

Completed

• Conditions: Peripheral Nervous System Diseases; HIV Infections

• Registration Number: NCT00046722
• Lead Sponsor: Center for Medicinal Cannabis Research

Brief Summary

To evaluate whether smoked marijuana reduces pain in people with HIV-related peripheral neuropathy.

Detailed Description

The study will include subjects with peripheral neuropathy caused either by HIV-disease or antiretroviral medication for the treatment of HIV. A neurologist will conduct a neurological and pain evaluation to determine eligibility for the study. Subjects who meet all eligibility criteria will be admitted to the General Clinical Research Center at San Francisco General Hospital for seven days. Subjects will be randomized (like a toss of a coin) to smoke marijuana or a placebo (cigarettes with no THC).

Study Timeline

• Study First Submitted: 2002-10-01
• Study First Submitted QC: 2002-10-02
• Study First Posted: 2002-10-03
• Study Start: 2003-01
• Study Completion: 2005-04
• Status Verified: 2007-06
• Last Update Submitted: 2007-06-12
• Last Update Posted: 2007-06-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in level of HIV-related neuropathic pain as recorded on a 100mm Visual Analog Scale.

Secondary Outcome Measures

Name	Time	Method
Change in level of experimentally-induced pain.

Trial Locations

Locations (1)

University of California, San Francisco Community Consortium; 🇺🇸 San Francisco, California, United States