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Influenza H1N1 Immunogenicity study - Tilburg Study

Conditions
o medical condition.Our aim is to study the immunogenicity against influenza virus H1N1(2009) before and after vaccination
Registration Number
EUCTR2009-017138-36-NL
Lead Sponsor
St Elisabeth Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
200
Inclusion Criteria

All the subjects are between 18 and 65 years of age
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

none

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: To determine the humoral and cellular immunity before and after vaccination with the Influenza A (H1N1) 2009 Monovalent MF59-Adjuvanted Vaccine.;Secondary Objective: To study the impact of earlier seasonal vaccination on the immune response against the influenza virus H1N1 (2009).<br><br>To determine the requirement of a second vaccination with Influenza A virus (H1N1) 2009 Monovalent MF59-Adjuvanted Vaccine.<br>;Primary end point(s): The study parameters for humoral immune response are hemagglutination-inhibition antibodies titers. Sera will be analyzed by a hemagglutination-inhibition (HAI) test, according to standard procedures.
Secondary Outcome Measures
NameTimeMethod
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