Effect of Strawberry Powder on Blood Pressure in Individuals With Pre-Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Change in blood pressure
研究概览
简要总结
The specific aim of the study is to determine whether a freeze dried powder provided by the California Strawberries Commission, can reduce blood pressure in patients with pre-hypertension. The powder is prepared by the California Strawberry Commission (CSC).
详细描述
Primarily, we would like to find out whether freeze dried strawberry powder lowers blood pressure. In addition we would like to know if the strawberry alters the subject's blood cholesterol and the ability of the subject's blood vessels to relax.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pre-hypertensive men and women (JNC 7 [The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure] criteria) between the ages of 25 and 65 years who have no clinical evidence/history of cardiovascular, respiratory, renal, gastrointestinal or hepatic disease.
排除标准
- •Subjects who:
- •are taking over the counter anti-oxidant supplements,
- •are taking prescription medications that may interfere with study procedures or endpoints,
- •have unusual dietary habits (eg., pica),
- •are actively losing weight or trying to lose weight,
- •are addicted to drugs or alcohol,
- •present with significant psychiatric or neurological disturbances,
- •have known allergies to strawberry, will be excluded from participating in this study.
- •Patients known to have glaucoma
- •Pregnant and/or lactating females
研究组 & 干预措施
Placebo Beverage
The placebo beverage is matched in energy, macronutrient composition and sensory properties to the active beverage, but is devoid of strawberry polyphenols.
干预措施: Placebo (Other)
Strawberry Beverage
The strawberry beverage is matched in energy, macronutrient composition and sensory properties to the placebo beverage, but contains strawberry polyphenols.
干预措施: Strawberry Beverage (Other)
结局指标
主要结局
Change in blood pressure
时间窗: 8 weeks
次要结局
- Change in low density lipoprotein (LDL) oxidation(8 weeks)
- Change in flow mediated dilation (FMD)(8 weeks)