Eating Behaviors in Shift Workers

Not Applicable

Active, not recruiting

• Conditions: Eating Behavior; Shift Work Type Circadian Rhythm Sleep Disorder
• Interventions: Behavioral: Portion size

• Registration Number: NCT04468672
• Lead Sponsor: Columbia University

Brief Summary

This study will compare eating behaviors and measures of hunger and fullness between day and night workers in order to better understand why night workers are at increased risk for obesity and related diseases.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-06-30
• Study First Submitted QC: 2020-07-10
• Study First Posted: 2020-07-13
• Study Start: 2020-12-14
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-03
• Last Update Posted: 2025-02-04
• Primary Completion: 2026-01
• Study Completion: 2026-06

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Work ~ 8-hour shifts during day or night on 3 or more consecutive days of the week
• BMI 19-35 kg/m^2
• Age 20-55 years of age
• Metabolically healthy
• Weight stable over previous 3 months
• Lives in New York City area

Exclusion Criteria

• Pregnant or less than 1 year postpartum at time of study
• Smoking
• History of drug or alcohol abuse
• Rotating shift work
• Habitual sleep duration of more than 6 hour per night
• Obstructive sleep apnea
• Transmeridian travel
• Type 2 diabetes
• Cardiovascular disease
• Hypertension
• Participation in diet or weight loss program in the 3 months prior to enrollment
• Psychiatric or sleep disorder
• Food allergies or intolerances
• Dislike of or unwillingness to eat test foods

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Day worker	Portion size	Men and women who work only day shift for at least 3 consecutive days of the week
Night worker	Portion size	Men and women who work only night shift for at least 3 consecutive days of the week

Primary Outcome Measures

Name	Time	Method
Food intake	24-hours intake period	Food by weight (g) in response to variations in portion served
Energy intake	24-hours intake period	Food by energy (kcal) in response to variations in portion served
Energy density consumed	24-hours intake period	Energy density consumed (kcal/g) in response to variations in portion served

Secondary Outcome Measures

Name	Time	Method
Appetite-regulating hormones	2-hours measurement period	Appetite-regulating hormones, including Glucagon-like-peptide 1 (GLP-1) and ghrelin will be analyzed from plasma from whole blood samples collected while fasted and at 30, 60, 90, and 120 min postprandial. Area under the curve of plasma concentrations will be calculated for each individual appetite-regulating hormone
Hunger and fullness	24-hours measurement period	Subjective measures related to hunger, fullness, and prospective consumption will be measured before and after meals via visual analog scales. The range of scores are 0 mm to 100 mm, with higher scores indicating greater feelings of the corresponding measure (e.g. greater hunger). Post-meal measures, adjusted for the corresponding pre-meal measure, will be analyzed as individual outcomes. Area under the curve will also be calculated for each measure.

Trial Locations

Locations (1)

Columbia University Irving Medical Center; 🇺🇸 New York, New York, United States