Collagen cross linking as adjunctive treatment for corneal ulcer.
Phase 3
- Conditions
- Health Condition 1: H160- Corneal ulcer
- Registration Number
- CTRI/2019/02/017601
- Lead Sponsor
- CHRISTIAN MEDICAL COLLEGE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)corneal ulcer size of 2mm to 6mm
2)smear and culture positive for bacteria and fungus
3)patients willing for inpatient care
Exclusion Criteria
1)suspected viral keratitis
2)suspected acanthamoeba keratitis
3)corneal thinning of more than 50%
4)pregnant woman
5)history of previous collagen cross linking
6)patients who are unable to understand and give consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Healing of corneal ulcer; end point-complete closure of the epithelial defect with no evidence of active infiltrate. <br/ ><br> <br/ ><br>Timepoint: during admission-as daily observation <br/ ><br>and on weekly review <br/ ><br>till healing of epithelial defect <br/ ><br>
- Secondary Outcome Measures
Name Time Method ilTimepoint: Nil