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A comparative study to ascertain efficacy of oral antifungal therapy and laser in fungal nail infection.

Phase 3
Conditions
Health Condition 1: L608- Other nail disorders
Registration Number
CTRI/2020/04/024536
Lead Sponsor
Dr Prasenjeet Mohanty
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Patients having one or more toenail and/or fingernail fungal infections of the following types: distal subungual onychomycosis, proximal subungual onychomycosis, superficial white/black onychomycosis, endonyx onychomycosis, total dystrophic type onychomycosis or mixed onychomycosis.

2.Patients with diabetes mellitus, immunocompromised patients, and organ transplant patients will be included, although we consider that these patient groups success rates could be considerably less.

Exclusion Criteria

1.Patients who used systemic antifungal or isotretinoin within 6months.

2.Permanent or semi-permanent discoloration of the nail plate (e.g. topical therapeutics, cosmetics or professional dye exposure) as they can cause various physiological changes to the nail plate in addition to discoloration.

3.Subungual hematoma, nevoid subungual formation, bacterial nail infections, and concomitant nail disorders such as psoriasis of nail plate, lichen planus and atopic dermatitis.

4.Fungal infections of other body parts.

5.Any generalized skin disease.

6.Pregnancy.

7.Patients having liver or renal disease.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
% of patients with excellent outcomeTimepoint: December 2019 to December 2020
Secondary Outcome Measures
NameTimeMethod
1. Species detection <br/ ><br>2. % of incomplete cure and relapse. <br/ ><br>3. Safety profile of interventionTimepoint: December 2019 to December 2020
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