Comparıson Of Electromyography Results Before And After Vıtamın D Treatment In Patıents Wıth Carpal Tunnel Syndrome
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 87
- 试验地点
- 1
- 主要终点
- electrophysiological scale.
研究概览
简要总结
Therefore, we aimed to evaluate the effectiveness of vitamin D replacement therapy on pain, electrophysiological parameters, ultrasonographic measurement results and functional status scales in CTS patients with low serum vitamin D levels.
详细描述
Introduction
Apart from its effect on bone health, vitamin D is also known to have beneficial effects on the neurological system. In studies, vitamin D levels were found to be low in patients with Carpal Tunnel Syndrome (CTS). However, studies examining the effects of vitamin D replacement on CTS are limited. Therefore, we aimed to evaluate the effectiveness of vitamin D replacement therapy on pain, electrophysiological parameters, ultrasonographic measurement results and functional status scales in CTS patients with low serum vitamin D levels. Materials and Methods: Our study was planned as an observational and analytical prospective. Vitamin D loading therapy was given to patients with serum vitamin D levels below 20ng/ml and mild-moderate CTS detected by electroneuromyography (ENMG). Patients with vitamin D levels above 20 ng/ml after 8 weeks were included in the study. Each patient was given a rest splint and exercise program. Patients were evaluated before and 3 months after treatment with electrophysiological, ultrasonographic, VAS, pinch-grip strength, two-point discrimination, monofilament test and Boston symptom severity scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-70 years old male or female gender
- •Those with mild to moderate CTS according to ENMG,
- •Vitamin D level <20.
排除标准
- •Severe CTS according to ENMG
- •Thenar region atrophy
- •diabetes mellitus,
- •rheumatoid arthritis,
- •hyperthyroidism,
- •hypothyroidism
- •Traumatic nerve injury, history of surgery
- •Polyneuropathy
- •Pregnancy
- •Severe psychiatric illness
- •Poor orientation and cooperation,
- •Injection (corticosteroid, ozone, stem cell...) applied for CTS treatment within 3 months
研究组 & 干预措施
Vitamin D in Carpal Tunnel Syndrome
干预措施: Vitamin D (Drug)
结局指标
主要结局
electrophysiological scale.
时间窗: at the baseline and immediately after treatment
Electrophysiological Evaluation: Neurowerk (SIGMA-Medizin-TechnicGmbH/Germany) brand ENMG device was used. Patients were evaluated at room temperature of approximately 25 °C. All measurements were made by the same doctor. Our clinic's reference values for the diagnosis of CTS are shown below
次要结局
- monofilament test(at the baseline and immediately after treatment)
研究者
Dr. Ayşe Güç
medical doctor
Kayseri Education and Research Hospital
