Exploratory study of test indices applicable to decisions regarding changes to treatment steps in adult patients with bronchial asthma
Not Applicable
- Conditions
- bronchial asthma
- Registration Number
- JPRN-UMIN000005406
- Lead Sponsor
- IAA Study Group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
1. Smoking history: >= 10 packs/yr 2. Current smokers (including patients who quit smoking < 1mth) 3. Patients with any of the following lung diseases: COPD, bronchiectasis, lung cancer, collagen disease, pulmonary hypertension, tuberculosis sequelae, diffuse panbronchiolitis, interstitial pneumonia 4. Patients who were hospitalized due to asthma in the past year, who had an emergency presentation of asthma in the past 3 months, or who received an infusion of steroids due to worsening of asthma in the past 3 months. 5.Other patients judged by the physician to be inappropriate for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Patients are classified into those who show aggravation of airway inflammation and those who do not after a dose reduction. A multivariate analysis is performed to identify the factors and parameters which account for the aggravation and increased eosinophil ratio (reflecting aggravation of airway inflammation) by evaluating patient demography prior to the dose reduction, absolute values of various parameters determined, and combinations thereof. 2) The correlation of sputum eosinophil count with FeNO level, ACQ score or GINA classification in asthma control is investigated.
- Secondary Outcome Measures
Name Time Method