NCT01575158已完成不适用
Citalopram vs Clomipramine vs Placebo in Recurrent Depression
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 59
- 主要终点
- 2 Hamilton Depression Rating Scale scores of at least 16 with one weeks interval or initiation of another antidepressant treatment
研究概览
简要总结
citalopram and clomipramine are better than placebo in preventing new episodes of depression in patients with recurrent depression
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with recurrent depression
- •Sustained response achieved (3 consecutive monthly ratings at the HDS below 13)after a treatment requiring index episode
排除标准
- •Contraindications to study medications
- •Pregnancy
- •Substance abuse
研究组 & 干预措施
citalopram
Experimental
citalopram
干预措施: Citalopram (Drug)
clomipramnine
Active Comparator
clomipramine
干预措施: Clomipramine (Drug)
placebo
Placebo Comparator
placebo
干预措施: placebo (Drug)
结局指标
主要结局
2 Hamilton Depression Rating Scale scores of at least 16 with one weeks interval or initiation of another antidepressant treatment
时间窗: 2 years of follow-up
次要结局
- Study termination due to adverse event or non-compliance(2 years of follow-up)
研究者
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