Comparative study of the effect of continuous administration of ETV (entecavir) or switching to TAF (tenofovir araphenamide fumarate) on renal function in cases with HBV infection during ETV administratio
Not Applicable
- Conditions
- Chronic hepatits B
- Registration Number
- JPRN-UMIN000034785
- Lead Sponsor
- Sapporo-Kosei General Hospital Department of Hepatology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients with CCr (Cockcroft-Gault) less than 15 mL/min. 2) Patients who are concurrently administering with other nucleoside or nucleotide analogue. 3) Patients who the doctor in charge considers inappropriate as the subject in this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in estimated glomerular filtration rate (eGFR) between the 2 groups from 48 weeks, 96 weeks, and 144 weeks after randomization.
- Secondary Outcome Measures
Name Time Method Difference in changes HBV markers between the 2 groups