Assessment of Safety and Hospital Resource Utilisation of Emergency Department Initiated Computed Tomography Coronary Angiography (CTCA) in Intermediate Risk Acute Coronary Syndrome (ACS) Patients: a Randomised Controlled Trial

Not Applicable

• Conditions: Acute Coronary Syndrome; Myocardial Infarction; Myocardial Injury; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12620000768998
• Lead Sponsor: The Royal Adelaide Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-07-27
• Last Update Posted: 3 August 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients will be eligible for enrolment into the study if they meet all of the following criteria upon presentation to the ED:
a) Symptoms of suspected ACS;
b) Grey Zone values for high sensitivity troponin T (hs-cTnT)*;
c) 18-70 years of age;
d) Weight is <150kg;
e) Have an eGFR >40ml/min;
f) Willing and able to give written informed consent.
*Initial troponin of <12ng/L and change of 3-4ng/L in 1 hour OR initial troponin between 13-51ng/L and a change of <5ng/L after 1 hour

Exclusion Criteria

Patients will be excluded from the study if they meet any of the following criteria upon presentation to the ED:
a) Presence of ST segment elevation on presenting ECG or other overtly ischaemic ECG changes
b) Presence of arrhymthia on presenting ECG
c) Have contraindications to CTCA including:
a. Pregnancy
b. Contrast allergy
d) Life expectancy of less than 12 months
e) Residing interstate or overseas

Study & Design

• Study Type: Interventional
• Study Design: Not specified