Exercise-training Before Coronary Artery Bypass Graft (CABG)

Not Applicable

Completed

• Conditions: Angina; Coronary Artery Disease
• Interventions: Behavioral: Exercise training

• Registration Number: NCT00218985
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The aim is to evaluate the effect of exercise training upon endothelial function in the mammary artery of patients who are scheduled for CABG, as well as study the functional properties of single cells isolated from a small biopsy of the left ventricle obtained during surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2005-09-20
• Study First Submitted QC: 2005-09-20
• Study First Posted: 2005-09-22
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-16
• Last Update Posted: 2018-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Scheduled for CABG both with and without heart failure

Exclusion Criteria

• Unstable angina
• Unable to walk on a treadmill (except those with heart failure who only will serve as a reference group)
• Participation in another study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
exercise training	Exercise training	-

Primary Outcome Measures

Name	Time	Method
Cardiovascular function and quality of life	Before and up to 1 year after intervention

Secondary Outcome Measures

Name	Time	Method
Cardiomyocyte structure and function	after the intervention period
Structure and function of cardiomyocytes	After the intervention period

Trial Locations

Locations (1)

Norwegian University of Science and Technology; 🇳🇴 Trondheim, Norway