Comparative study between two medications named Lignocaine and Dexmedetomidine as intravenous infusion, for pain during and after the surgical procedure, in patients undergoing general anaesthesia for craniotomy and excision of supratentorial brain tumors
Not Applicable
- Conditions
- Health Condition 1: C710- Malignant neoplasm of cerebrum, except lobes and ventricles
- Registration Number
- CTRI/2023/03/050843
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA physical status I & II patients
2. BMI 18-30
3. Tumour size <5cm on CT/MRI scan of head
4. Glasgow Coma Score (GCS) 15/15
Exclusion Criteria
1. Features of mass effect (midline shift, herniation) on brain scan.
2. Tumour near Eloquent area of brain requiring neurophysiological monitoring.
3. History of cardiovascular disease (uncontrolled hypertension, brady- or tachy- arrhythmias, heart blocks, coronary heart disease, history of myocardial infarction, CABG, heart failure etc.).
4. History of uncontrolled respiratory, endocrine or renal diseases (TB, asthma, COPD, DM, Hypo or hyperthyroidism, acute or chronic renal failure, electrolyte imbalance etc)
5. History of psychiatric illness and /or medication.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the time for first postoperative rescue analgesia between lidocaine, dexmedetomidine and saline groups in patients undergoing supratentorial tumour resection under inhalation anaesthesia.Timepoint: First postoperative rescue analgesia
- Secondary Outcome Measures
Name Time Method