ICU patient response to tracheal suctioning with placebo, lignocaine or dexmedetomidine
Phase 4
- Conditions
- Health Condition 1: null- ICU patients
- Registration Number
- CTRI/2012/08/002898
- Lead Sponsor
- Kasturba Hospital KMC Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
All patients that have a tracheal tube in situ in IC
Exclusion Criteria
1.Patients with known or suspected allergy to any of the study drugs (dexmedetomidine, lidocaine)
2.Patients with seizure disorder
3.Patients receiving neuromuscular blockade / with known neuromuscular disease
4.Patients who were hypotensive requiring more than one inotrope / vasopressor
5.Patients that were delirious or had disease condition that would confuse the behaviour assessment, such as decerebrate posturing
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umerical rating scale score <br/ ><br>Behavioural response score <br/ ><br>Haemodynamic fluctuations of 20% from baselineTimepoint: Baseline, at one minute interval for five minutes starting from the point of tracheal suctioning and at 10th and 15th minute following tracheal suctioning. <br/ ><br>Behavioural response and numerical rating was assessed just prior to tracheal suctioning and in the following minute after tracheal suctioning
- Secondary Outcome Measures
Name Time Method Complications <br/ ><br>Arrhythmias, desaturation <br/ ><br>Timepoint: During study period, that is within 15 minutes after tracheal suctioning