Abnormal Placenta Plant Disease Early Diagnosis and Individualized Treatment Research

• Conditions: Scarred Uterus

• Registration Number: NCT02946749
• Lead Sponsor: Shanghai First Maternity and Infant Hospital

Brief Summary

As the "two-child" policy implementation, caesarean women's clinical pregnancy is a huge problem again, Especially the placenta planting abnormal disease is a serious threat to the maternal health and life. Through this research, the investigators can obtain relevant epidemiological data and provide objective data for the department of public health policy; Predicting an placenta abnormal planting early diagnosis model was constructed, it will fill the blank in this field, and high-risk groups in the early stages of pregnancy will be taken proper disposal, the related complications will be reduced to ensure the safety of maternal.

Detailed Description

This study focus on four hands: (1) to investigate different types of gestational sac implantation for pregnancy in caesarean women of childbearing age;(2) to explore the relationship between abnormal placenta planting disease in middle-late pregnancy and the different types of scar pregnancy (3) to explore the the value of ultrasound and serological markers for early diagnosis of placenta planting disease from scar pregnancy; (4) to compare the end and the influence of health economy of different termination method on scar pregnancy.

Study Timeline

• Study First Submitted: 2016-10-22
• Study First Submitted QC: 2016-10-25
• Study First Posted: 2016-10-27
• Study Start: 2016-12
• Status Verified: 2017-07
• Last Update Submitted: 2017-07-30
• Last Update Posted: 2017-08-01
• Primary Completion: 2018-12
• Study Completion: 2018-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 3000

Inclusion Criteria

• Single pregnancies with once cesarean section history
• see a doctor before gestational 8 weeks in our study center
• will continue to pregnancy, high patient compliance

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Exclusion Criteria

• twins or multiple pregnancies
• hysteromyoma or adenomyoma stripping history
• history of intrauterine adhesions

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Placenta implanted	up to 37 gestational weeks

Secondary Outcome Measures

Name	Time	Method
Placenta previa	up to 37 gestational weeks