Early Prediction of Placenta Accreta by Ultrasound and Color Doppler

Completed

• Conditions: Placenta Accreta
• Interventions: Device: two-dimensional ultrasound and color Doppler

• Registration Number: NCT03032770
• Lead Sponsor: Assiut University

Brief Summary

Placenta accreta is a substantially life threatening condition and one of the causes of maternal morbidity and mortality in the world. According to study done in United Kingdom, The estimated incidence of placenta accreta/increta/percreta was 1.7 per 10,000 maternities overall and 577 per 10,000 in women with both a previous cesarean delivery and placenta previa. in a tertiary south Italian center, The incidence increased from 0.12% during the 1970s, to 0.31% during the 2000s.While in United States of America, the prevalence of placenta accreta was 3.7 per 1000 deliveries.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Study First Submitted: 2017-01-24
• Study First Submitted QC: 2017-01-24
• Study First Posted: 2017-01-26
• Primary Completion: 2019-12-31
• Study Completion: 2020-03-31
• Status Verified: 2020-05
• Last Update Submitted: 2020-05-11
• Last Update Posted: 2020-05-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 148

Inclusion Criteria

1. Low implantation of the gestational sac (<4 cm from external os) by transvaginal ultrasound
2. Presence of placental lakes by transvaginal ultrasound
3. Disruption of placental-myometrial interface by transvaginal ultrasound
4. Trophoblast overlapping a uterine scar (Cesarean section, myomectomy) by transvaginal ultrasound
5. Intraplacental dilated vessels by Doppler ultrasound
6. Turbulent blood flows by Doppler ultrasound
7. Greatly increased periplacental vascularity by Doppler ultrasound

Exclusion Criteria

a) Cases far away from our hospital and expected to be lost to be followed. b) Pregnant women who will refuse to Participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
placenta accreta	two-dimensional ultrasound and color Doppler	Having at least one sign suggestive of placenta accreta
normal placenta	two-dimensional ultrasound and color Doppler	Never having any of the signs suggestive of placenta accreta

Primary Outcome Measures

Name	Time	Method
Confirmation of occurrence of placenta accreta during delivery.	duration of pregnancy

Trial Locations

Locations (1)

Assiut University; 🇪🇬 Assiut, Egypt