The effects of a cognition enhancer (CILTEP) on a cognitive test battery and EEG in middle-aged and old volunteers
Completed
- Conditions
- ong-term memory
- Registration Number
- NL-OMON21957
- Lead Sponsor
- Maastricht University, Department of Neuropsychology & Psychopharmacology
- Brief Summary
Pending
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
1. Male or female;
2. 30 to 40 or 60 to 75 years of age;
Exclusion Criteria
1. history of cardiac, hepatic, renal, pulmonary, neurological, gastrointestinal, haematological, or psychiatric ilness or a first-degree relative with a psychiatric disorder or a history with a psychiatric disorder;
2. excessive drinking (> 20 glasses of alcohol containing beverages a week);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To establish the effects of CILTEP on cognition, especially memory. The main cognitive tests that will be used are the verbal learning task (VLT), in which participants need to memorize words that are presented on a screen, and the spatial pattern separation test, using photographs to assess episodic memory.
- Secondary Outcome Measures
Name Time Method Performance in several other cognitive tests will be our secondary objective. We will examine the effects of CILTEP on working memory performance using an n-back task, on information processing speed using the digit symbol substitution test (DSST), on motor speed using a simple and choice reaction time task (SRT and CRT, respectively), on attention and concept shifting using the trail making test, and on response inhibition and focused attention using the Stroop. A sensory gating paradigm is included to examine the effect of our treatment on specific ERP components related to basic auditory processing. <br>