weaning from nasal continuous positive airway pressure in preterm infants

Not Applicable

• Conditions: Respiratory distress syndrome of newborn.; Respiratory distress of newborn

• Registration Number: IRCT20180915041040N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Gestational age equal to or less than 32 weeks and birth weight equal to or less than 1800 gr
Starting NCPAP from first hours of birth to treat respiratory distress syndrome
Treatment with NCPAP after weaning from positive pressure ventilation via endotracheal route
The newborn should be under treatment with NCPAP for at least 24 hours
5th minute APGAR score above 4

Exclusion Criteria

Documented congenital heart anomalies (except for small atrial septal defect, patent foramen ovale, and patent ductus arteriosus (PDA))
definite or possible neuromuscular disease
definite or possible syndrome
need for surgery
transfer to other hospital
patients weighing less than 750 g at the time of randomization
intraventricular hemorrhage (grade above 2)
lung hypoplasia
other life-threatening congenital anomalies
thoracic or airway anomalies
need for mechanical ventilation before NCPAP removal

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Successful NCPAP weaning in the first attempt. Timepoint: After first attempt to NCPAP weaning. Method of measurement: Number of attempts.

Secondary Outcome Measures

Name	Time	Method
The frequency of weaning. Timepoint: After each time of weaning from the device. Method of measurement: Document.