The neural basis of congitive-emotional processing in people with an at-risk mental state for developing psychosis
Recruiting
- Conditions
- psychosisschizophrenia10039628
- Registration Number
- NL-OMON33062
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
- healthy individuals, male and female with IQ in the normal range and with normal or corrected to normal vision.
- between 18 and 45 years old
Exclusion Criteria
- neurological problems (incl. epilepsy)
- use of drugs that may influence the task
- contra indications for fMRI will lead to exclusion, fMRI-exclusion criteria:
- MR incompatible implants in the body (such as ear prothesis or other metal implants)
- any risk of having metal particles in the eye
- tattoos containing red pigments
- (suspected) pregnancy
- claustrophobia
- the refusal to be informed of structural brain abornamilities that could be detected during the experiment.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>In this study brain activation during cognitieve processing will be<br /><br>investigated in two separate sessions, separated by 8 months. Questionnaire<br /><br>scores will be linked to brain activation. Through diagnostic interviews and<br /><br>symptom evalutions 2 years after the first fMRI scan will be conducted, to<br /><br>evaluate whether fMRI activation was predictive of the clinical state 2 years<br /><br>later.</p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>