Perioperative Colloid vs Crystalloid in Patients Undergoing Colorectal Surgery
Phase 4
Terminated
- Conditions
- Surgery, Colorectal
- Interventions
- Drug: balanced crystalloid
- Registration Number
- NCT01303250
- Lead Sponsor
- University Hospital Muenster
- Brief Summary
The primary purpose of this study is to determine the effect of a balanced 6%hydroxyethyl starch 130/0.4 vs. a balanced crystalloid in colorectal surgery. The intraoperative fluid management will be given to optimize the stroke volume variation \<= 12%.
The investigators hypothesize that patients in the intervention group will need less fluid administration be optimal hemodynamic stabilized.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 31
Inclusion Criteria
- patients undergoing elective colorectal surgery
- minimum age 18 years
- informed consent
Exclusion Criteria
- patients with severe cardiomyopathy or severe heart failure
- history of coagulation disorders
- intracranial hemorrhage
- patients with severe cardiovascular or respiratory disorders
- renal insufficiency
- severe liver diseases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group 2 balanced crystalloid A balanced crystalloid will be used Group 1 balanced 6% hydroxyethylstarch 130/0.4 A balanced hydroxyethyl starch 130/0.4 will be used
- Primary Outcome Measures
Name Time Method Total amount of administered fluids intraoperatively Total amount of administered fluids intraoperatively that is necessary to keep patients optimal hemodynamic stabilized
- Secondary Outcome Measures
Name Time Method Incidence of surgery related complications day 28 and 90 postoperatively
Trial Locations
- Locations (1)
University Hospital Muenster
🇩🇪Muenster, Germany